Prevention
Health And Interception
Therapeutics
Aiming to Prevent Lung Cancer With the Drug Oral Iloprost
Clinical Stage Pharmaceutical Company in Seattle
PHAIT, Inc. is a clinical-stage private pharmaceutical company in Seattle. We aim to prevent lung cancer, the world’s #1 cancer killer, by reversing the malignant progression of bronchial dysplasia. Our seasoned team leads clinical trials for Iloprost to gain FDA approval to market oral iloprost for patients at high risk for lung cancer, patients with resected early-stage lung cancer, and patients with COPD.
PHAIT.org (Predictive Health Analytics Institute) is a 501(c)(3) that serves as the non-profit complement to PHAIT.com for the purpose of research, clinical studies, and education for cancer prevention that utilizes interventional therapies.
Iloprost
Iloprost (oral form) targets all patients at risk of lung cancer. It addresses a significantly larger market than patients who already have lung cancer. In the U.S. alone, there are around 14.6 million patients.
Iloprost is an anti-tumorigenic and anti-inflammatory prostacyclin derivative created by Schering (Bayer). It functions by activating PPAR through the Frizzled-9 receptor, which prevents angiogenesis, epithelial to mesenchymal transition, and cell proliferation. This drug prevents or reverses bronchial dysplasia, the precancerous condition that represents the window of cancer interception.
Well-tolerated
For decades, Iloprost has been used worldwide in a wide range of treatments.
Demonstrated Effectiveness
Iloprost in the oral form has been successfully used in clinical studies supported by the National Cancer Institute and University of Colorado research for the purpose of chemoprevention of lung cancer. Due to the necessity to maintain high and constant systemic levels of the medication, only oral Iloprost demonstrated effectiveness to reduce dysplasia that can lead to lung cancer.
We are also working with another business to create a non-invasive companion diagnostic test for bronchial dysplasia patients who do not exhibit symptoms.